Clinical Trials

Clinical research has the potential to improve people's lives.

Good medicine is that which is based on evidence. And clinical research trials are how that evidence is gathered about new medications and medical devices. As such, almost every medicine you or someone you love takes today was once part of a clinical trial. But clinical trials are not just how medicines and devices get approved. The truth is that many people have been helped as a result of having access to leading-edge care, which they otherwise wouldn’t have. After all, for virtually every medication and medical device on the market today, the first people to be helped were people who were part of the study. Studies conducted at Advanced Respiratory and Sleep Medicine, PLLC include trials that have contributed to the approval of medications such as Breo, Trelegy, Stiolto, Breztri, Sunosi, Xywav, Wakix, and Lumryz to name a few.

Advanced Respiratory and Sleep Medicine (ARSM) partners with pharmaceutical and medical device companies to research new products and technologies that may someday impact peoples’ lives. The ARSM team includes Thomas Stern, MD, MS; Asha Stern, MD, MPH; Todd M. Thompson, PA-C; and Felix Kurniawan, MS.

Dr. Thomas Stern, and Dr. Asha Stern were the principal investigators in more than 60 clinical trials. These include studies in obstructive sleep apnea, narcolepsy, COPD, asthma, and bronchiectasis.

Current Studies by Indication

Asthma

A Study to Assess the Effect of Dexpramipexole in Adolescents and Adults With Severe Eosinophilic Asthma. (EXHALE-2)

A Study to Assess the Effect of Dexpramipexole in Adolescents and Adults With Eosinophilic Asthma (EXHALE-4)

Study to Assess PT010 in Adult and Adolescent Participants With Inadequately Controlled Asthma (LOGOS)

Study Assessing the Long-term Effect of Dupilumab on Prevention of Lung Function Decline in Adult Patients With Uncontrolled Moderate to Severe Asthma

A Study of GSK3511294 (Depemokimab) Compared With Mepolizumab or Benralizumab in Participants With Severe Asthma With an Eosinophilic Phenotype (NIMBLE)

Chronic Obstructive Pulmonary Disease (COPD)

A Study Comparing Efficacy, Safety and Tolerability of the Fixed Dose Triple Combination CHF 5993 With the Fixed Dose Dual Combination CHF 1535 in Subjects With COPD (TRITON)

A 52-week, Placebo- and Active- Controlled (Roflumilast, Daliresp® 500µg) Study to Evaluate the Efficacy and Safety of Two Doses of CHF6001 DPI (Tanimilast) as add-on to Maintenance Triple Therapy in Subjects With COPD and Chronic Bronchitis. (PILLAR)

A Study to Evaluate the Long-Term Safety of Astegolimab in Participants With Chronic Obstructive Pulmonary Disease (COPD)

Study to Assess the Efficacy, Safety, and Tolerability of SAR440340/​REGN3500/​Itepekimab in Chronic Obstructive Pulmonary Disease (COPD) (AERIFY-2)

Idiopathic Hypersomnia

Ph4 PSG Combined JZP258-407

Narcolepsy

A Switch Study From High-Sodium Oxybate to XYWAV to Evaluate Changes in Blood Pressure in Participants With Narcolepsy

Ph4 PSG Combined JZP258-407

Obstructive sleep apnea

Parallel Arm Trial of AD109 and Placebo With Patients With OSA (LunAIRo)

Contact us to take part in a clinical trial.

If you are interested in participating in a clinical trial at Advanced Respiratory and Sleep Medicine, PLLC please fill out this form,

You can contact: Felix Kurniawan, Site Director/Certified Clinical Research Coordinator, Telephone: 704-248-0000 ext1012, Email: felix@arsmnc.com